Chromatic Pupillometry in Children.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_FF9BBD7E20EE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Chromatic Pupillometry in Children.
Journal
Frontiers in neurology
Author(s)
Crippa S.V., Pedrosa Domellöf F., Kawasaki A.
ISSN
1664-2295 (Print)
ISSN-L
1664-2295
Publication state
Published
Issued date
2018
Peer-reviewed
Oui
Volume
9
Pages
669
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Chromatic pupillometry is a technique that is increasingly used to assess retinal disorders. As age may be one of the various factors which can influence the pupillary light reaction, this study aimed to evaluate the pupil responses to colored light stimuli in the pediatric population. Fifty-three children with normal vision and without any history of ocular disorders were tested with a portable pupillometer. Four test sequences were used: five dim blue (470 nm) stimuli presented in half log steps ranging from -3.15 to -1.15 log cd/m <sup>2</sup> after 3 min of dark adaptation, five red (622 nm) stimuli of -1.15, -0.7, -0.15, 0.3, and 0.85 log cd/m <sup>2</sup> after 1 min light adaptation, one bright blue stimulus of 2.2 log cd/m <sup>2</sup> and one bright red of 2 log cd/m <sup>2</sup> . The results were grouped by age: a younger group included 27 children aged from 3 to 10 years old and an older group included 26 from 10 and 1 month to 18 years old. The younger group had a smaller pupil diameter after dark adaptation compared with the older group. A linear regression defining the photopic threshold showed that younger subjects had a higher threshold, e.g., needed a brighter red stimulus to evoke a threshold pupil response comparable that of subjects. Age thus seems to influence outer retinal sensitivity at least as evaluated by the pupillary photopic threshold intensity. The post-illumination pupillary reaction was used as a marker of intrinsic melanopsin activity and did not show any difference between the two age groups.
Keywords
children, chromatic pupillometry, growth, pupil, pupillary light reaction
Pubmed
Web of science
Open Access
Yes
Create date
11/09/2018 7:31
Last modification date
20/08/2019 16:29
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