HIV and innate immunity ? a genomics perspective

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Ressource 1Download: BIB_F9ECBF31CC79.P001.pdf (517.00 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_F9ECBF31CC79
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
HIV and innate immunity ? a genomics perspective
Journal
F1000prime Reports
Author(s)
Rausell A., McLaren P.J., Telenti A.
ISSN
2051-7599 (Electronic)
ISSN-L
2051-7599
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
5
Pages
29
Language
english
Notes
Publication types: Review Article ; review-article Identifiant PubMed Central: PMC3732074
Abstract
Innate immunity is a theme of increasing interest for HIV research. However, the term is overstretched to cover biological barriers, cellular systems, soluble factors, signaling pathways, and effectors and is inconsistently applied. A clearer semantic classification of the components of innate immunity is needed, which will have direct relevance to the interpretation of human genome variation. Here, we discuss genomic approaches that can assist in re-defining the perimeter of innate immunity. We place particular emphasis on the characteristics of effectors of the intracellular defense against HIV and other pathogens.
Pubmed
Create date
11/07/2016 10:04
Last modification date
20/08/2019 16:25
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