Patients at risk of complications of Staphylococcus aureus bloodstream infection.

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Serval ID
serval:BIB_F2C1CC892374
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Patients at risk of complications of Staphylococcus aureus bloodstream infection.
Journal
Clinical Infectious Diseases
Author(s)
del Rio A., Cervera C., Moreno A., Moreillon P., Miró J.M.
ISSN
1537-6591 (Electronic)
ISSN-L
1058-4838
Publication state
Published
Issued date
2009
Volume
48 Suppl 4
Pages
S246-S253
Language
english
Abstract
Staphylococcus aureus is one of the most common causative pathogens of bloodstream infections (BSIs). In approximately one-half of patients with S. aureus BSI, no portal of entry can be documented. This group of patients has a high risk of developing septic metastases. Similarly, patient populations at high risk of S. aureus BSI and BSI-associated complications include patients receiving hemodialysis, injection drug users, patients with diabetes, and patients with preexisting cardiac conditions or other comorbidities. One of the most severe complications of S. aureus BSI is infective endocarditis, and S. aureus is now the most common cause of infective endocarditis in the developed world. Patients with methicillin-resistant S. aureus BSI or infective endocarditis have higher rates of mortality, compared with patients with methicillin-susceptible S. aureus infection. Nasal carriage is the most important source of S. aureus BSI. Better eradication and control strategies, including nasal decolonization and more-active antibiotics, are needed to combat S. aureus BSIs.
Keywords
Bacteremia/complications, Bacteremia/drug therapy, Carrier State, Endocarditis/etiology, Humans, Methicillin-Resistant Staphylococcus aureus/isolation & purification, Nasal Cavity/microbiology, Risk Factors, Staphylococcal Infections/complications, Staphylococcal Infections/drug therapy, Staphylococcus aureus/isolation & purification
Pubmed
Web of science
Open Access
Yes
Create date
03/02/2010 16:48
Last modification date
14/02/2022 7:57
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