Independent drug bulletins to promote the prescription of appropriate drugs: a necessary but difficult task.

Details

Ressource 1Download: BIB_EAA2A9B17688.pdf (648.46 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_EAA2A9B17688
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
Title
Independent drug bulletins to promote the prescription of appropriate drugs: a necessary but difficult task.
Journal
Bulletin of the World Health Organization
Author(s)
Burnand Bernard
ISSN
1564-0604 (Electronic)
ISSN-L
0042-9686
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
91
Number
6
Pages
391-391A
Language
english
Notes
Publication types: Journal Article; PDF : editorial
Abstract
Drug treatments constitute a substantial portion of all health-care interventions. Despite their notable benefits, however, drug treatments are beyond the reach of sizable population groups and in someparts of the world there is little access to safe and effective medications even though new drugs are constantly being developed.
The effectiveness and safety of newly developed drugs are often viewed too optimistically. According to a Cochrane systematic review published recently, new drugs are seldom found to be substantially better than existing treatments. However, because of lack of full and transparent access to the protocols of many clinical trials, compounded by publication bias and selective reporting of their findings, the true effectiveness of many drugs remains unknown. It is a fact that the results of trials are more likely to be published if the findings are favourable than if they are not. In addition, some measured outcomes are never reported, which generally results in an overestimation of effectiveness and an underestimation of harmful effects.
Pubmed
Web of science
Open Access
Yes
Create date
02/11/2011 12:22
Last modification date
20/08/2019 16:13
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