A structural MRI study of motor conversion disorder: evidence of reduction in thalamic volume.

Details

Ressource 1Download: BIB_E036DBD94C33.P001.pdf (230.65 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_E036DBD94C33
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A structural MRI study of motor conversion disorder: evidence of reduction in thalamic volume.
Journal
Journal of Neurology, Neurosurgery, and Psychiatry
Author(s)
Nicholson T.R., Aybek S., Kempton M.J., Daly E.M., Murphy D.G., David A.S., Kanaan R.A.
ISSN
1468-330X (Electronic)
ISSN-L
0022-3050
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
85
Number
2
Pages
227-229
Language
english
Notes
Publication types: Journal Article
Abstract
OBJECTIVE: To investigate potential abnormalities in subcortical brain structures in conversion disorder (CD) compared with controls using a region of interest (ROI) approach.
METHODS: Fourteen patients with motor CD were compared with 31 healthy controls using high-resolution MRI scans with an ROI approach focusing on the basal ganglia, thalamus and amygdala. Brain volumes were measured using Freesurfer, a validated segmentation algorithm.
RESULTS: Significantly smaller left thalamic volumes were found in patients compared with controls when corrected for intracranial volume. These reductions did not vary with handedness, laterality, duration or severity of symptoms.
CONCLUSIONS: These differences may reflect a primary disease process in this area or be secondary effects of the disorder, for example, resulting from limb disuse. Larger, longitudinal structural imaging studies will be required to confirm the findings and explore whether they are primary or secondary to CD.
Pubmed
Web of science
Open Access
Yes
Create date
15/01/2014 14:36
Last modification date
20/08/2019 16:04
Usage data