Schizotypal perceptual aberrations of time: correlation between score, behavior and brain activity.

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Serval ID
serval:BIB_D90CF2B50BF6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Schizotypal perceptual aberrations of time: correlation between score, behavior and brain activity.
Journal
Plos One
Author(s)
Arzy S., Mohr C., Molnar-Szakacs I., Blanke O.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
6
Number
1
Pages
e16154
Language
english
Abstract
A fundamental trait of the human self is its continuum experience of space and time. Perceptual aberrations of this spatial and temporal continuity is a major characteristic of schizophrenia spectrum disturbances--including schizophrenia, schizotypal personality disorder and schizotypy. We have previously found the classical Perceptual Aberration Scale (PAS) scores, related to body and space, to be positively correlated with both behavior and temporo-parietal activation in healthy participants performing a task involving self-projection in space. However, not much is known about the relationship between temporal perceptual aberration, behavior and brain activity. To this aim, we composed a temporal Perceptual Aberration Scale (tPAS) similar to the traditional PAS. Testing on 170 participants suggested similar performance for PAS and tPAS. We then correlated tPAS and PAS scores to participants' performance and neural activity in a task of self-projection in time. tPAS scores correlated positively with reaction times across task conditions, as did PAS scores. Evoked potential mapping and electrical neuroimaging showed self-projection in time to recruit a network of brain regions at the left anterior temporal cortex, right temporo-parietal junction, and occipito-temporal cortex, and duration of activation in this network positively correlated with tPAS and PAS scores. These data demonstrate that schizotypal perceptual aberrations of both time and space, as reflected by tPAS and PAS scores, are positively correlated with performance and brain activation during self-projection in time in healthy individuals along the schizophrenia spectrum.
Pubmed
Web of science
Open Access
Yes
Create date
06/04/2011 10:01
Last modification date
20/08/2019 15:58
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