Molecular Epidemiology of Pseudomonas aeruginosa in the Intensive Care Units - A Review.

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State: Public
Version: author
Serval ID
serval:BIB_D557DC4A0988
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Molecular Epidemiology of Pseudomonas aeruginosa in the Intensive Care Units - A Review.
Journal
Open Microbiology Journal
Author(s)
Blanc D.S., Francioli P., Zanetti G.
ISSN
1874-2858
Publication state
Published
Issued date
2007
Volume
1
Pages
8-11
Language
english
Notes
Publication types: Journal Article
Abstract
Pseudomonas aeruginosa is one of the leading nosocomial pathogens in intensive care units (ICU). This opportunist pathogen is commonly recovered from moist environments, and is also found colonizing 2.6 to 24% of hospitalized patients. We reviewed the recent literature that used highly discriminatory typing methods to precisely identify the reservoirs and modes of transmission of this microorganism in the ICU setting. In most ICUs, the endogenous flora was suspected to be the main source of infection compared to exogenous sources (other patients, the contaminated environment such as sinks or taps). However, the percentage of endogenous versus exogenous sources might vary considerably from one setting to another. Reasons for this include the compliance of health care workers to infection control measures, the contamination of the environment, and probably also the biology of the pathogen (intrinsic fitness factors). As P. aerugi-nosa is ubiquitous in the environment and colonizes up to 15% of hospitalized patients, eradication of the reservoir is difficult, if not impossible. Therefore, efforts should primarily focus on reinforcement of infection control measures to limit its transmission.
Keywords
Psudomonas aeroginosa
Pubmed
Web of science
Open Access
Yes
Create date
06/02/2008 14:41
Last modification date
20/08/2019 15:55
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