Updates in Rhea - an expert curated resource of biochemical reactions.

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State: Public
Version: Final published version
Serval ID
serval:BIB_D4F55C24D893
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Updates in Rhea - an expert curated resource of biochemical reactions.
Journal
Nucleic acids research
Author(s)
Morgat A., Lombardot T., Axelsen K.B., Aimo L., Niknejad A., Hyka-Nouspikel N., Coudert E., Pozzato M., Pagni M., Moretti S., Rosanoff S., Onwubiko J., Bougueleret L., Xenarios I., Redaschi N., Bridge A.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Publication state
Published
Issued date
04/01/2017
Peer-reviewed
Oui
Volume
45
Number
D1
Pages
D415-D418
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the description of metabolic networks. Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as well as additional reactions, including spontaneously occurring reactions, using entities from the ChEBI (Chemical Entities of Biological Interest) ontology of small molecules. Here we describe developments in Rhea since our last report in the database issue of Nucleic Acids Research. These include the first implementation of a simple hierarchical classification of reactions, improved coverage of the IUBMB Enzyme Nomenclature list and additional reactions through continuing expert curation, and the development of a new website to serve this improved dataset.

Pubmed
Open Access
Yes
Create date
29/12/2016 13:25
Last modification date
20/08/2019 15:54
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