Health utility indexes in patients with acute coronary syndromes.

Details

Ressource 1Download: BIB_ACE092D8F42E.P001.pdf (622.96 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_ACE092D8F42E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Health utility indexes in patients with acute coronary syndromes.
Journal
Open Heart
Author(s)
Gencer B., Rodondi N., Auer R., Nanchen D., Räber L., Klingenberg R., Pletscher M., Jüni P., Windecker S., Matter C.M., Lüscher T.F., Mach F., Perneger T.V., Girardin F.R.
ISSN
2053-3624 (Electronic)
ISSN-L
2053-3624
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
3
Number
1
Pages
e000419
Language
english
Abstract
BACKGROUND: Acute coronary syndromes (ACS) have been associated with lower health utilities (HUs) compared with the general population. Given the prognostic improvements after ACS with the implementation of coronary angiography (eg, percutaneous coronary intervention (PCI)), contemporary HU values derived from patient-reported outcomes are needed.
METHODS: We analysed data of 1882 patients with ACS 1 year after coronary angiography in a Swiss prospective cohort. We used the EuroQol five-dimensional questionnaire (EQ-5D) and visual analogue scale (VAS) to derive HU indexes. We estimated the effects of clinical factors on HU using a linear regression model and compared the observed HU with the average values of individuals of the same sex and age in the general population.
RESULTS: Mean EQ-5D HU 1-year after coronary angiography for ACS was 0.82 (±0.16) and mean VAS was 0.77 (±0.18); 40.9% of participants exhibited the highest utility values. Compared with population controls, the mean EQ-5D HU was similar (expected mean 0.82, p=0.58) in patients with ACS, but the mean VAS was slightly lower (expected mean 0.79, p<0.001). Patients with ACS who are younger than 60 years had lower HU than the general population (<0.001). In patients with ACS, significant differences were found according to the gender, education and employment status, diabetes, obesity, heart failure, recurrent ischaemic or incident bleeding event and participation in cardiac rehabilitation (p<0.01).
CONCLUSIONS: At 1 year, patients with ACS with coronary angiography had HU indexes similar to a control population. Subgroup analyses based on patients' characteristics and further disease-specific instruments could provide better sensitivity for detecting smaller variations in health-related quality of life.
Pubmed
Open Access
Yes
Create date
14/06/2016 17:18
Last modification date
20/08/2019 15:16
Usage data