Therapy modifications in response to poorly controlled hypertension, dyslipidemia, and diabetes mellitus.

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Version: author
Serval ID
serval:BIB_6D35CE04DF0F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Therapy modifications in response to poorly controlled hypertension, dyslipidemia, and diabetes mellitus.
Journal
Annals of internal medicine
Author(s)
Rodondi N., Peng T., Karter A.J., Bauer D.C., Vittinghoff E., Tang S., Pettitt D., Kerr E.A., Selby J.V.
ISSN
1539-3704
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
144
Number
7
Pages
475-84
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
BACKGROUND: Poorly controlled cardiovascular risk factors are common. Evaluating whether physicians respond appropriately to poor risk factor control in patients may better reflect quality of care than measuring proportions of patients whose conditions are controlled. OBJECTIVES: To evaluate therapy modifications in response to poor control of hypertension, dyslipidemia, or diabetes in a large clinical population. DESIGN: Retrospective cohort study within an 18-month period in 2002 to 2003. SETTING: Kaiser Permanente of Northern California. PATIENTS: 253,238 adult members with poor control of 1 or more of these conditions. MEASUREMENTS: The authors assessed the proportion of patients with poor control who experienced a change in pharmacotherapy within 6 months, and they defined "appropriate care" as a therapy modification or return to control without therapy modification within 6 months. RESULTS: A total of 64% of patients experienced modifications in therapy for poorly controlled systolic blood pressure, 71% for poorly controlled diastolic blood pressure, 56% for poorly controlled low-density lipoprotein cholesterol level, and 66% for poorly controlled hemoglobin A1c level. Most frequent modifications were increases in number of drug classes (from 70% to 84%) and increased dosage (from 15% to 40%). An additional 7% to 11% of those with poorly controlled blood pressure, but only 3% to 4% of those with elevated low-density lipoprotein cholesterol level or hemoglobin A1c level, returned to control without therapy modification. Patients with more than 1 of the 3 conditions, higher baseline values, and target organ damage were more likely to receive "appropriate care." LIMITATIONS: Patient preferences and suboptimal adherence to therapy were not measured and may explain some failures to act. CONCLUSIONS: As an additional measure of the quality of care, measuring therapy modifications in response to poor control in a large population is feasible. Many patients with poorly controlled hypertension, dyslipidemia, or diabetes had their therapy modified and, thus, seemed to receive clinically "appropriate care" with this new quality measure.
Keywords
Adult, Aged, California, Diabetic Angiopathies, Female, Humans, Hyperlipidemias, Hypertension, Male, Middle Aged, Patient Compliance, Patient Satisfaction, Quality Indicators, Health Care, Retrospective Studies, Risk Factors
Pubmed
Web of science
Create date
28/01/2008 12:01
Last modification date
20/08/2019 14:26
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