Comment on "Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2".

Details

Ressource 1Download: BIB_54872E5E59FB.P001.pdf (1366.65 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_54872E5E59FB
Type
Article: article from journal or magazin.
Publication sub-type
Letter (letter): Communication to the publisher.
Collection
Publications
Institution
Title
Comment on "Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2".
Journal
Science Translational Medicine
Author(s)
Vassalli A., Li S., Tafti M.
ISSN
1946-6242 (Electronic)
ISSN-L
1946-6234
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
7
Number
314
Pages
314le2
Language
english
Abstract
Did hypocretin receptor 2 autoantibodies cause narcolepsy with hypocretin deficiency in Pandemrix-vaccinated children, as suggested by Ahmed et al.? Using newly developed mouse models to report and inactivate hypocretin receptor expression, Vassalli et al. now show that hypocretin neurons (whose loss causes narcolepsy) do not express hypocretin autoreceptors, raising questions to the interpretation of Ahmed et al.'s findings.
Keywords
Narcolepsy, Influenza, Hypocretin/Orexin Receptor, Vaccine
Pubmed
Web of science
Open Access
Yes
Create date
03/12/2015 13:21
Last modification date
20/08/2019 14:09
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