Imaging of Lemierre Syndrome in children and young adultsA case-series analysis

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Version: After imprimatur
Serval ID
serval:BIB_24A49932A155
Type
A Master's thesis.
Publication sub-type
Master (thesis) (master)
Collection
Publications
Institution
Title
Imaging of Lemierre Syndrome in children and young adultsA case-series analysis
Author(s)
Trachsel L.
Director(s)
Gudinchet F.
Institution details
Université de Lausanne, Faculté de biologie et médecine
Publication state
Accepted
Issued date
2012
Language
english
Number of pages
21
Abstract
Background / Purpose :
Lemierre Syndrome (LS) is defined by a recent oro-pharangeal infection, the clinical
presence or radiological demonstration of internal jugular vein (IJV) thrombosis and
documented anaerobe germ, principally Fusobacterium necrophorum (Fn) leading to
septicaemia and septic embolization. It is a rare infection described since 1900 and it nearly disappeared since the beginning of the antibiotic area. Even if it is seldom described in the literature, this infection is reappearing in the last 10 years, either because of the increase of antibiotic resistance or by modification of antibiotic prescription. The aim of this study is to describe the role of medical imaging in the diagnosis, staging and follow up of Lemierre syndrome, as well as to describe the ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) findings of this rare disease.
Patients and methods :
Radiological and medical files of patients diagnosed with Lemierre syndrome in the past 6 years at CHUV hospital were analysed retrospectively. The CT scan, US, colour Doppler US (CDUS) and MRI examinations that were performed have been examined so as to define their specific imaging findings.
Results
IJV thrombosis was demonstrated in 2 cases by US, by CT in 6 cases and MRI in one case. Septic pulmonary emboli were detected by CT in 5 patients. Complications of the LS were depicted by MR in one case and by CT in 1 case.
Conclusion :
In the appropriate clinical settings, US, CT or MR evidence of IJV thrombosis and chest CT suggestive of septic emboli, should lead the physician to consider the diagnosis of LS. As a consequence, imaging allows a faster diagnosis and a more efficient treatment of this infection, which in case of insufficient therapy can lead to death.
Create date
25/06/2013 15:26
Last modification date
20/08/2019 14:02
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