Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies.

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Ressource 1Download: nutrients-09-00517.pdf (1077.57 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_215D122FF452
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies.
Journal
Nutrients
Author(s)
Kosinski C., Jornayvaz F.R.
ISSN
2072-6643 (Electronic)
ISSN-L
2072-6643
Publication state
Published
Issued date
19/05/2017
Peer-reviewed
Oui
Volume
9
Number
5
Pages
0
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
The treatment of obesity and cardiovascular diseases is one of the most difficult and important challenges nowadays. Weight loss is frequently offered as a therapy and is aimed at improving some of the components of the metabolic syndrome. Among various diets, ketogenic diets, which are very low in carbohydrates and usually high in fats and/or proteins, have gained in popularity. Results regarding the impact of such diets on cardiovascular risk factors are controversial, both in animals and humans, but some improvements notably in obesity and type 2 diabetes have been described. Unfortunately, these effects seem to be limited in time. Moreover, these diets are not totally safe and can be associated with some adverse events. Notably, in rodents, development of nonalcoholic fatty liver disease (NAFLD) and insulin resistance have been described. The aim of this review is to discuss the role of ketogenic diets on different cardiovascular risk factors in both animals and humans based on available evidence.

Keywords
Animals, Cardiovascular Diseases/etiology, Cardiovascular Diseases/prevention & control, Diabetes Mellitus, Type 2/complications, Diabetes Mellitus, Type 2/diet therapy, Diet, Ketogenic/adverse effects, Diet, Ketogenic/methods, Dietary Carbohydrates/administration & dosage, Humans, Insulin Resistance, Non-alcoholic Fatty Liver Disease/etiology, Obesity/complications, Obesity/diet therapy, Risk Factors, NAFLD, cardiovascular risk factors, fibroblast growth factor (FGF21), insulin resistance, ketogenic diets, obesity, type 2 diabetes
Pubmed
Web of science
Open Access
Yes
Create date
30/05/2017 16:10
Last modification date
20/08/2019 12:57
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