Central Serous Chorioretinopathy Misdiagnosed as Posterior Uveitis and the Vicious Circle of Corticosteroid Therapy

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Version: Final published version
Serval ID
serval:BIB_093F27219BB8
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Central Serous Chorioretinopathy Misdiagnosed as Posterior Uveitis and the Vicious Circle of Corticosteroid Therapy
Journal
Journal of Ophthalmic and Vision Research
Author(s)
Papadia , Jeannin , Herbort 
ISSN
2008-2010 (Print)
2008-322X (Electronic)
ISSN-L
2008-322X
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
10
Number
3
Pages
303-308
Language
english
Notes
Publication types: Original Article ; research-article Identifiant PubMed Central: PMC4687265
Abstract
PURPOSE: To determine the proportion of patients with central serous chorioretinopathy (CSCR) mistaken for posterior uveitis and to identify the deleterious consequences.
METHODS: Charts of 1,657 patients admitted in the section of inflammatory eye diseases at the Center for Ophthalmic Specialized Care (COS) in Lausanne, Switzerland from 1995 to 2013 were reviewed. CSCR cases misdiagnosed as posterior uveitis or those with superimposed disease due to steroid therapy for uveitis were studied. Delay in diagnosis, specific erroneous uveitis diagnosis and evolution of the disease were also evaluated. Retrospectively, the most useful means for a correct diagnosis of CSCR were the original fluorescein angiography (FA), indocyanine green angiography (ICGA) and optical coherence tomography (OCT) when available.
RESULTS: Out of a total of 1,657 patients, 15 (0.9%) cases with CSCR were identified. These included 12 subjects misdiagnosed as posterior uveitis and 3 uveitis subjects with superimposed CSCR following corticosteroid therapy for uveitis. The presentation of the disease was largely influenced by improper and continued use of corticosteroids.
CONCLUSION: CSCR is a rare but not negligible misdiagnosis in posterior uveitis representing approximately 1% of subjects from a collective series of uveitis cases at a referral center. Investigative measures such as FA, ICGA and OCT are crucial for reaching a correct diagnosis and avoiding disease aggravation due to corticosteroid therapy.
Keywords
Central Serous Chorioretinopathy, Fluorescein Angiography, Indocyanine Green Angiography, Optical Coherence Tomography, Uveitis
Pubmed
Open Access
Yes
Create date
11/10/2016 15:29
Last modification date
20/08/2019 12:31
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